Prognostic Value of Risk Score and Urinary Markers in Idiopathic Membranous Nephropathy

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Prognostic value of risk score and urinary markers in idiopathic membranous nephropathy.

BACKGROUND AND OBJECTIVES Accurate prediction of prognosis may improve management of patients with idiopathic membranous nephropathy. This study compared the Toronto Risk Score and urinary low-molecular weight proteins. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS One hundred four patients with biopsy-proven idiopathic membranous nephropathy who presented between 1995 and 2008 with a well-pr...

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Urinary IgG excretion as a prognostic factor in idiopathic membranous nephropathy.

In membranous nephropathy it would be of great value to be able to identify in an early phase patients at highest risk for disease progression, since potentially toxic treatment could then be restricted to these patients only. We measured renal hemodynamics, serum proteins and urinary protein excretion in 22 patients with membranous nephropathy, nephrotic syndrome and normal renal function (end...

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Urinary IgG excretion as a prognostic factor in idiopathic membranous nephropathy

In membranous nephropathy it would be of great value to be able to identify in an early phase patients at highest risk for disease progression, since potentially toxic treatment could then be restricted to these patients only. We measured renal hemodynamics, serum proteins and urinary pro­ tein excretion in 22 patients with membranous nephropathy, nephrotic syndrome and normal renal function (e...

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Treatment of idiopathic membranous nephropathy.

Exciting progress recently has been made in our understanding of idiopathic membranous nephropathy, as well as treatment of this disease. Here, we review important advances regarding the pathogenesis of membranous nephropathy. We will also review the current approach to treatment and its limitations and will highlight new therapies that are currently being explored for this disease including Ri...

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Analysis of the prognostic risk factors of idiopathic membranous nephropathy using a new surrogate end-point

Idiopathic membranous nephropathy (IMN) is one of the most common causes of nephrotic syndrome (NS) in adults. The latest study of the chronic kidney disease-prognosis consortium showed that a 30% decrease in the estimated glomerular filtration rate (eGFR) within 2 years could cover more patients and showed a better correlation with end-stage renal disease (ESRD), as compared with serum creatin...

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ژورنال

عنوان ژورنال: Clinical Journal of the American Society of Nephrology

سال: 2012

ISSN: 1555-9041,1555-905X

DOI: 10.2215/cjn.00670112